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Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum
Protein folding in the endoplasmic reticulum is a complex process whose malfunction is implicated in disease and aging. Using the cell’s endogenous sensor (the unfolded protein response), we identified several hundred yeast genes with roles in endoplasmic reticulum folding and systematically charact...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877488/ https://ncbi.nlm.nih.gov/pubmed/19325107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1167983 |
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