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Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum

Protein folding in the endoplasmic reticulum is a complex process whose malfunction is implicated in disease and aging. Using the cell’s endogenous sensor (the unfolded protein response), we identified several hundred yeast genes with roles in endoplasmic reticulum folding and systematically charact...

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Hlavní autoři: Jonikas, Martin C., Collins, Sean R., Denic, Vladimir, Oh, Eugene, Quan, Erin M., Schmid, Volker, Weibezahn, Jimena, Schwappach, Blanche, Walter, Peter, Weissman, Jonathan S., Schuldiner, Maya
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877488/
https://ncbi.nlm.nih.gov/pubmed/19325107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1167983
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