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Defining the Glycan Destruction Signal for Endoplasmic Reticulum-Associated Degradation

The endoplasmic reticulum (ER) must target potentially toxic misfolded proteins for retrotranslocation and proteasomal degradation while avoiding the destruction of productive folding intermediates. For luminal proteins, this discrimination typically depends not only on the folding status of a polyp...

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Bibliografski detalji
Glavni autori: Quan, Erin M., Kamiya, Yukiko, Kamiya, Daiki, Denic, Vladimir, Weibezahn, Jimena, Kato, Koichi, Weissman, Jonathan S.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873636/
https://ncbi.nlm.nih.gov/pubmed/19111666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.11.017
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