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Defining the Glycan Destruction Signal for Endoplasmic Reticulum-Associated Degradation
The endoplasmic reticulum (ER) must target potentially toxic misfolded proteins for retrotranslocation and proteasomal degradation while avoiding the destruction of productive folding intermediates. For luminal proteins, this discrimination typically depends not only on the folding status of a polyp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873636/ https://ncbi.nlm.nih.gov/pubmed/19111666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.11.017 |
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