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Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

To maintain protein homeostasis in secretory compartments, eukaryotic cells harbor a quality control system that monitors protein folding and protein complex assembly in the endoplasmic reticulum (ER). Proteins that do not fold properly or integrate into cognate complexes are degraded by ER-associat...

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Detalhes bibliográficos
Main Authors: Clerc, Simone, Hirsch, Christian, Oggier, Daniela Maria, Deprez, Paola, Jakob, Claude, Sommer, Thomas, Aebi, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615083/
https://ncbi.nlm.nih.gov/pubmed/19124653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200809198
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