The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation

Asn-linked glycans (N-glycans) play important roles in the quality control (QC) of glycoprotein folding in the endoplasmic reticulum (ER) lumen and in ER-associated degradation (ERAD) of proteins by cytosolic proteasomes. A UDP-Glc:glycoprotein glucosyltransferase glucosylates N-glycans of misfolded...

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Main Authors: Banerjee, Sulagna, Vishwanath, Prashanth, Cui, Jike, Kelleher, Daniel J., Gilmore, Reid, Robbins, Phillips W., Samuelson, John
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905923/
https://ncbi.nlm.nih.gov/pubmed/17606910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704862104
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