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Emerging Structural Insights into Glycoprotein Quality Control Coupled with N-Glycan Processing in the Endoplasmic Reticulum

In the endoplasmic reticulum (ER), the sugar chain is initially introduced onto newly synthesized proteins as a triantennary tetradecasaccharide (Glc(3)Man(9)GlcNAc(2)). The attached oligosaccharide chain is subjected to stepwise trimming by the actions of specific glucosidases and mannosidases. In...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Satoh, Tadashi, Yamaguchi, Takumi, Kato, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272264/
https://ncbi.nlm.nih.gov/pubmed/25647580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20022475
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