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Structural insight into substrate recognition by the endoplasmic reticulum folding-sensor enzyme: crystal structure of third thioredoxin-like domain of UDP-glucose:glycoprotein glucosyltransferase

The endoplasmic reticulum (ER) possesses a protein quality control system that supports the efficient folding of newly synthesized glycoproteins. In this system, a series of N-linked glycan intermediates displayed on proteins serve as quality tags. The ER folding-sensor enzyme UDP-glucose:glycoprote...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Tong, Satoh, Tadashi, Kato, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255179/
https://ncbi.nlm.nih.gov/pubmed/25471383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07322
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