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The Role of the Lipid Bilayer in Tau Aggregation

Tau is a microtubule associated protein whose aggregation is implicated in a number of neurodegenerative diseases. We investigate the mechanism by which anionic lipid vesicles induce aggregation of tau in vitro using K18, a fragment of tau corresponding to the four repeats of the microtubule binding...

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Autores principales: Elbaum-Garfinkle, Shana, Ramlall, Trudy, Rhoades, Elizabeth
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877329/
https://ncbi.nlm.nih.gov/pubmed/20513417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.013
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