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The Role of the Lipid Bilayer in Tau Aggregation

Tau is a microtubule associated protein whose aggregation is implicated in a number of neurodegenerative diseases. We investigate the mechanism by which anionic lipid vesicles induce aggregation of tau in vitro using K18, a fragment of tau corresponding to the four repeats of the microtubule binding...

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Hlavní autoři: Elbaum-Garfinkle, Shana, Ramlall, Trudy, Rhoades, Elizabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877329/
https://ncbi.nlm.nih.gov/pubmed/20513417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.013
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