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Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity

In fission yeast, RNAi directs heterochromatin formation at centromeres, telomeres, and the mating type locus. Noncoding RNAs transcribed from repeat elements generate siRNAs that are incorporated into the Argonaute-containing RITS complex and direct it to nascent homologous transcripts. This leads...

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Detalhes bibliográficos
Main Authors: Bayne, Elizabeth H., White, Sharon A., Kagansky, Alexander, Bijos, Dominika A., Sanchez-Pulido, Luis, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Ponting, Chris P., Rappsilber, Juri, Allshire, Robin C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875855/
https://ncbi.nlm.nih.gov/pubmed/20211136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.01.038
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