Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast

Heterochromatin formation at fission yeast centromeres is directed by RNA interference (RNAi). Noncoding transcripts derived from centromeric repeats are processed into small interfering RNAs (siRNAs) that direct the RNA-induced transcriptional silencing (RITS) effector complex to engage centromere...

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Bibliografische gegevens
Hoofdauteurs: Bayne, Elizabeth H., Portoso, Manuela, Kagansky, Alexander, Kos-Braun, Isabelle C., Urano, Takeshi, Ekwall, Karl, Alves, Flavia, Rappsilber, Juri, Allshire, Robin C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585287/
https://ncbi.nlm.nih.gov/pubmed/18948543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164029
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