Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast

Heterochromatin formation at fission yeast centromeres is directed by RNA interference (RNAi). Noncoding transcripts derived from centromeric repeats are processed into small interfering RNAs (siRNAs) that direct the RNA-induced transcriptional silencing (RITS) effector complex to engage centromere...

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Main Authors: Bayne, Elizabeth H., Portoso, Manuela, Kagansky, Alexander, Kos-Braun, Isabelle C., Urano, Takeshi, Ekwall, Karl, Alves, Flavia, Rappsilber, Juri, Allshire, Robin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585287/
https://ncbi.nlm.nih.gov/pubmed/18948543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164029
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