Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast

RNA interference (RNAi) is widespread in eukaryotes and regulates gene expression transcriptionally or post-transcriptionally. In fission yeast, RNAi is tightly coupled to template transcription and chromatin modifications that establish heterochromatin in cis. Exogenous double-stranded RNA (dsRNA)...

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Detalhes bibliográficos
Main Authors: Simmer, Femke, Buscaino, Alessia, Kos-Braun, Isabelle C, Kagansky, Alexander, Boukaba, Abdelhalim, Urano, Takeshi, Kerr, Alastair R W, Allshire, Robin C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828748/
https://ncbi.nlm.nih.gov/pubmed/20062003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.273
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