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Heterochromatin and RNAi Are Required to Establish CENP-A Chromatin at Centromeres

Heterochromatin is defined by distinct posttranslational modifications on histones, such as methylation of histone H3 at lysine 9 (H3K9), which allows heterochromatin protein 1 (HP1)–related chromodomain proteins to bind. Heterochromatin is frequently found near CENP-A chromatin, which is the key de...

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Detalhes bibliográficos
Main Authors: Folco, Hernan Diego, Pidoux, Alison L., Urano, Takeshi, Allshire, Robin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586718/
https://ncbi.nlm.nih.gov/pubmed/18174443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1150944
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