Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification

Noncoding RNAs can modulate gene expression by directing modifications to histones that alter chromatin structure. In fission yeast, siRNAs produced via the RNAi pathway direct modifications associated with heterochromatin formation. siRNAs associate with the RNAi effector protein Argonaute 1 (Ago1)...

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Detalhes bibliográficos
Main Authors: He, Chao, Pillai, Sreerekha S., Taglini, Francesca, Li, Fudong, Ruan, Ke, Zhang, Jiahai, Wu, Jihui, Shi, Yunyu, Bayne, Elizabeth H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666757/
https://ncbi.nlm.nih.gov/pubmed/23613586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212155110
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