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GENETIC CHANGES DURING LABORATORY PROPAGATION: COPY NUMBER AT THE RETICULOCYTE BINDING PROTEIN 1 LOCUS OF PLASMODIUM FALCIPARUM
Comparative genomic hybridization studies have revealed elevated copy number (CN) at the reticulocyte binding protein 1 gene (PfRh1) in fast growing lab-adapted parasites, while genetic manipulation demonstrates a causal link between cell invasion and PfRh1 CN. We therefore examined PfRh1 copy numbe...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875377/ https://ncbi.nlm.nih.gov/pubmed/20363264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.03.015 |
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