Adaptive Copy Number Evolution in Malaria Parasites

Copy number polymorphism (CNP) is ubiquitous in eukaryotic genomes, but the degree to which this reflects the action of positive selection is poorly understood. The first gene in the Plasmodium folate biosynthesis pathway, GTP-cyclohydrolase I (gch1), shows extensive CNP. We provide compelling evide...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nair, Shalini, Miller, Becky, Barends, Marion, Jaidee, Anchalee, Patel, Jigar, Mayxay, Mayfong, Newton, Paul, Nosten, François, Ferdig, Michael T., Anderson, Tim J. C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2008
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570623/
https://ncbi.nlm.nih.gov/pubmed/18974876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000243
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