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Population Structure Shapes Copy Number Variation in Malaria Parasites

If copy number variants (CNVs) are predominantly deleterious, we would expect them to be more efficiently purged from populations with a large effective population size (N(e)) than from populations with a small N(e). Malaria parasites (Plasmodium falciparum) provide an excellent organism to examine...

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Détails bibliographiques
Publié dans:Mol Biol Evol
Auteurs principaux: Cheeseman, Ian H., Miller, Becky, Tan, John C., Tan, Asako, Nair, Shalini, Nkhoma, Standwell C., De Donato, Marcos, Rodulfo, Hectorina, Dondorp, Arjen, Branch, Oralee H., Mesia, Lastenia Ruiz, Newton, Paul, Mayxay, Mayfong, Amambua-Ngwa, Alfred, Conway, David J., Nosten, François, Ferdig, Michael T., Anderson, Tim J. C.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760083/
https://ncbi.nlm.nih.gov/pubmed/26613787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv282
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