Population Structure Shapes Copy Number Variation in Malaria Parasites

If copy number variants (CNVs) are predominantly deleterious, we would expect them to be more efficiently purged from populations with a large effective population size (N(e)) than from populations with a small N(e). Malaria parasites (Plasmodium falciparum) provide an excellent organism to examine...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Cheeseman, Ian H., Miller, Becky, Tan, John C., Tan, Asako, Nair, Shalini, Nkhoma, Standwell C., De Donato, Marcos, Rodulfo, Hectorina, Dondorp, Arjen, Branch, Oralee H., Mesia, Lastenia Ruiz, Newton, Paul, Mayxay, Mayfong, Amambua-Ngwa, Alfred, Conway, David J., Nosten, François, Ferdig, Michael T., Anderson, Tim J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760083/
https://ncbi.nlm.nih.gov/pubmed/26613787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv282
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