Population Structure Shapes Copy Number Variation in Malaria Parasites

If copy number variants (CNVs) are predominantly deleterious, we would expect them to be more efficiently purged from populations with a large effective population size (N(e)) than from populations with a small N(e). Malaria parasites (Plasmodium falciparum) provide an excellent organism to examine...

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Publicat a:Mol Biol Evol
Autors principals: Cheeseman, Ian H., Miller, Becky, Tan, John C., Tan, Asako, Nair, Shalini, Nkhoma, Standwell C., De Donato, Marcos, Rodulfo, Hectorina, Dondorp, Arjen, Branch, Oralee H., Mesia, Lastenia Ruiz, Newton, Paul, Mayxay, Mayfong, Amambua-Ngwa, Alfred, Conway, David J., Nosten, François, Ferdig, Michael T., Anderson, Tim J. C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760083/
https://ncbi.nlm.nih.gov/pubmed/26613787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv282
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