Population Structure Shapes Copy Number Variation in Malaria Parasites

If copy number variants (CNVs) are predominantly deleterious, we would expect them to be more efficiently purged from populations with a large effective population size (N(e)) than from populations with a small N(e). Malaria parasites (Plasmodium falciparum) provide an excellent organism to examine...

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Bibliografiska uppgifter
I publikationen:Mol Biol Evol
Huvudupphovsmän: Cheeseman, Ian H., Miller, Becky, Tan, John C., Tan, Asako, Nair, Shalini, Nkhoma, Standwell C., De Donato, Marcos, Rodulfo, Hectorina, Dondorp, Arjen, Branch, Oralee H., Mesia, Lastenia Ruiz, Newton, Paul, Mayxay, Mayfong, Amambua-Ngwa, Alfred, Conway, David J., Nosten, François, Ferdig, Michael T., Anderson, Tim J. C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760083/
https://ncbi.nlm.nih.gov/pubmed/26613787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv282
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