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Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52–ssDNA complexes
Rad52 promotes the annealing of complementary strands of DNA bound by replication protein A (RPA) during discrete repair pathways. Here, we used a fluorescence resonance energy transfer (FRET) between two fluorescent dyes incorporated into DNA substrates to probe the mechanism by which human Rad52 (...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875008/ https://ncbi.nlm.nih.gov/pubmed/20081207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1249 |
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