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Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture

Rad51, Rad52, and RPA play central roles in homologous DNA recombination. Rad51 mediates DNA strand exchange, a key reaction in DNA recombination. Rad52 has two distinct activities: to recruit Rad51 onto single-strand (ss)DNA that is complexed with the ssDNA-binding protein, RPA, and to anneal compl...

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Détails bibliographiques
Auteurs principaux: Sugiyama, Tomohiko, Kantake, Noriko, Wu, Yun, Kowalczykowski, Stephen C
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679760/
https://ncbi.nlm.nih.gov/pubmed/17093500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601412
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