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Rad51 Protein Controls Rad52-mediated DNA Annealing

In Saccharomyces cerevisiae, Rad52 protein plays an essential role in the repair of DNA double-stranded breaks (DSBs). Rad52 and its orthologs possess the unique capacity to anneal single-stranded DNA (ssDNA) complexed with its cognate ssDNA-binding protein, RPA. This annealing activity is used in m...

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Detalhes bibliográficos
Main Authors: Wu, Yun, Kantake, Noriko, Sugiyama, Tomohiko, Kowalczykowski, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386943/
https://ncbi.nlm.nih.gov/pubmed/18337252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801097200
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