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Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding
RAD52 protein has an important role in homology-directed DNA repair by mediating RAD51 nucleoprotein filament formation on single-stranded DNA (ssDNA) protected by replication protein-A (RPA) and annealing of RPA-coated ssDNA. In human, cellular response to DNA damage includes phosphorylation of RAD...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160658/ https://ncbi.nlm.nih.gov/pubmed/21804533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.238 |
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