Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion

BACKGROUND AND PURPOSE: The volatile anaesthetic isoflurane protects the heart from ischaemia and reperfusion (I/R) injury when applied at the onset of reperfusion [anaesthetic postconditioning (APoC)]. However, the mechanism of APoC-mediated protection is unknown. In this study, we examined the eff...

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Main Authors: Pravdic, D, Mio, Y, Sedlic, F, Pratt, PF, Warltier, DC, Bosnjak, ZJ, Bienengraeber, M
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers with Commentaries
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874845/
https://ncbi.nlm.nih.gov/pubmed/20423337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00698.x
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