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A Data Integration Approach to Mapping OCT4 Gene Regulatory Networks Operative in Embryonic Stem Cells and Embryonal Carcinoma Cells

It is essential to understand the network of transcription factors controlling self-renewal of human embryonic stem cells (ESCs) and human embryonal carcinoma cells (ECs) if we are to exploit these cells in regenerative medicine regimes. Correlating gene expression levels after RNAi-based ablation o...

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Bibliografiske detaljer
Main Authors: Jung, Marc, Peterson, Hedi, Chavez, Lukas, Kahlem, Pascal, Lehrach, Hans, Vilo, Jaak, Adjaye, James
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873957/
https://ncbi.nlm.nih.gov/pubmed/20505756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010709
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