Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification.

Partial monosomy of the short arm of chromosome 1 is the most consistent cytogenetic abnormality found in human neuroblastomas, but its overall frequency and significance are unclear. Using a panel of chromosome-1-specific DNA probes that identify restriction fragment length polymorphisms, we demons...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Fong, C T, Dracopoli, N C, White, P S, Merrill, P T, Griffith, R C, Housman, D E, Brodeur, G M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2566996/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3753
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