PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis

Tumor necrosis factor-α (TNF-α) is a cytokine that has an important role in immunity and inflammation by inducing cellular responses such as apoptosis. The transcription factor nuclear factor-κB (NF-κB) can paradoxically suppress and promote apoptosis in response to TNF-α. In this study, we found th...

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Detalhes bibliográficos
Main Authors: Wang, P, Qiu, W, Dudgeon, C, Liu, H, Huang, C, Zambetti, GP, Yu, J, Zhang, L
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872087/
https://ncbi.nlm.nih.gov/pubmed/19444283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.51
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