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PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis
Tumor necrosis factor-α (TNF-α) is a cytokine that has an important role in immunity and inflammation by inducing cellular responses such as apoptosis. The transcription factor nuclear factor-κB (NF-κB) can paradoxically suppress and promote apoptosis in response to TNF-α. In this study, we found th...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872087/ https://ncbi.nlm.nih.gov/pubmed/19444283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.51 |
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