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Single TNFα trimers mediating NF-κB activation: stochastic robustness of NF-κB signaling

BACKGROUND: The NF-κB regulatory network controls innate immune response by transducing variety of pathogen-derived and cytokine stimuli into well defined single-cell gene regulatory events. RESULTS: We analyze the network by means of the model combining a deterministic description for molecular spe...

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Detalhes bibliográficos
Main Authors: Lipniacki, Tomasz, Puszynski, Krzysztof, Paszek, Pawel, Brasier, Allan R, Kimmel, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222661/
https://ncbi.nlm.nih.gov/pubmed/17925009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-376
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