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Solvation Response Along the Reaction Coordinate in the Active Site of Ketosteroid Isomerase

A light-activated reaction analog has been developed to mimic the catalytic reaction cycle of Δ(5)-3-ketosteroid isomerase in order to probe the functionally relevant protein solvation response to the catalytic charge transfer. Δ(5)-3-ketosteroid isomerase from Pseudomonas putida catalyses a C-H bon...

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Bibliografiske detaljer
Main Authors: Childs, William, Boxer, Steven G.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871671/
https://ncbi.nlm.nih.gov/pubmed/20397697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1007849
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