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FOXO3a Regulates Glycolysis via Transcriptional Control of Tumor Suppressor TSC1
Akt signal transduction induces coordinated increases in glycolysis and apoptosis resistance in a broad spectrum of cancers. Downstream of Akt, the FoxO transcription factors regulate apoptosis via Bim, but the contributions of FoxOs in regulating Akt-induced glycolysis are not well described. We fi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871464/ https://ncbi.nlm.nih.gov/pubmed/20371605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121871 |
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