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ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis

Elevated glycolysis is a common metabolic trait of cancer, but what drives such metabolic reprogramming remains incompletely clear. We report here a novel transcriptional repressor-mediated negative regulation of glycolysis. ZBTB7A, a member of the POK (POZ/BTB and Krüppel) transcription repressor f...

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Detalhes bibliográficos
Main Authors: Liu, Xue-Song, Haines, Jenna E., Mehanna, Elie K., Genet, Matthew D., Ben-Sahra, Issam, Asara, John M., Manning, Brendan D., Yuan, Zhi-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197949/
https://ncbi.nlm.nih.gov/pubmed/25184678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.245910.114
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