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ZBTB7A suppresses melanoma metastasis by transcriptionally repressing MCAM

The excessive metastatic propensity of melanoma makes it the most deadly form of skin cancer, yet the underlying mechanism of metastasis remains elusive. Here, mining of cancer genome datasets discovered a frequent loss of chromosome 19p13.3 and associated down-regulation of the zinc finger transcri...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Liu, Xue-Song, Genet, Matthew D, Haines, Jenna E, Mehanna, Elie K, Wu, Shaowei, Chen, Hung-I Harry, Chen, Yidong, Qureshi, Abrar A, Han, Jiali, Chen, Xiang, Fisher, David E, Pandolfi, Pier Paolo, Yuan, Zhi-Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543565/
https://ncbi.nlm.nih.gov/pubmed/25995384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0169
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