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FOXO-regulated transcription restricts overgrowth of Tsc mutant organs
FOXO is thought to function as a repressor of growth that is, in turn, inhibited by insulin signaling. However, inactivating mutations in Drosophila melanogaster FOXO result in viable flies of normal size, which raises a question over the involvement of FOXO in growth regulation. Previously, a growt...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265581/ https://ncbi.nlm.nih.gov/pubmed/18299344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710100 |
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