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Prodrug Activation by Cryptosporidium Thymidine Kinase
Cryptosporidium spp. cause acute gastrointestinal disease that can be fatal for immunocompromised individuals. These protozoan parasites are resistant to conventional antiparasitic chemotherapies and the currently available drugs to treat these infections are largely ineffective. Genomic studies sug...
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Glavni autori: | , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871459/ https://ncbi.nlm.nih.gov/pubmed/20231284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.101543 |
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