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Prodrug Activation by Cryptosporidium Thymidine Kinase

Cryptosporidium spp. cause acute gastrointestinal disease that can be fatal for immunocompromised individuals. These protozoan parasites are resistant to conventional antiparasitic chemotherapies and the currently available drugs to treat these infections are largely ineffective. Genomic studies sug...

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Bibliografski detalji
Glavni autori: Sun, Xin E., Sharling, Lisa, Muthalagi, Mani, Mudeppa, Devaraja G., Pankiewicz, Krzysztof W., Felczak, Krzysztof, Rathod, Pradipsinh K., Mead, Jan, Striepen, Boris, Hedstrom, Lizbeth
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871459/
https://ncbi.nlm.nih.gov/pubmed/20231284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.101543
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