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Structural Basis for Hydroxycholesterols as Natural Ligands of Orphan Nuclear Receptor RORγ

The retinoic acid-related orphan receptor γ (RORγ) has important roles in development and metabolic homeostasis. Although the biological functions of RORγ have been studied extensively, no ligands for RORγ have been identified, and no structure of RORγ has been reported. In this study, we showed tha...

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Autors principals: Jin, Lihua, Martynowski, Dariusz, Zheng, Songyang, Wada, Taira, Xie, Wen, Li, Yong
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870936/
https://ncbi.nlm.nih.gov/pubmed/20203100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0507
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