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Structural Basis for Hydroxycholesterols as Natural Ligands of Orphan Nuclear Receptor RORγ

The retinoic acid-related orphan receptor γ (RORγ) has important roles in development and metabolic homeostasis. Although the biological functions of RORγ have been studied extensively, no ligands for RORγ have been identified, and no structure of RORγ has been reported. In this study, we showed tha...

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Detalhes bibliográficos
Main Authors: Jin, Lihua, Martynowski, Dariusz, Zheng, Songyang, Wada, Taira, Xie, Wen, Li, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870936/
https://ncbi.nlm.nih.gov/pubmed/20203100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0507
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