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Structural Basis for Hydroxycholesterols as Natural Ligands of Orphan Nuclear Receptor RORγ
The retinoic acid-related orphan receptor γ (RORγ) has important roles in development and metabolic homeostasis. Although the biological functions of RORγ have been studied extensively, no ligands for RORγ have been identified, and no structure of RORγ has been reported. In this study, we showed tha...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Endocrine Society
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2870936/ https://ncbi.nlm.nih.gov/pubmed/20203100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0507 |
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