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The Tumor Suppressor p53: From Structures to Drug Discovery

Even 30 years after its discovery, the tumor suppressor protein p53 is still somewhat of an enigma. p53's intimate and multifaceted role in the cell cycle is mirrored in its equally complex structural biology that is being unraveled only slowly. Here, we discuss key structural aspects of p53 fu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joerger, Andreas C., Fersht, Alan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869527/
https://ncbi.nlm.nih.gov/pubmed/20516128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000919
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