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Quaternary structures of tumor suppressor p53 and a specific p53–DNA complex
The homotetrameric tumor suppressor p53 consists of folded core and tetramerization domains, linked and flanked by intrinsically disordered segments that impede structure analysis by x-ray crystallography and NMR. Here, we solved the quaternary structure of human p53 in solution by a combination of...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941468/ https://ncbi.nlm.nih.gov/pubmed/17620598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705069104 |
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