microRNA/Argonaute 2 regulates nonsense-mediated messenger RNA decay

Imperfect base-pairing between microRNA (miRNA) and the 3′-untranslated region of target messenger RNA (mRNA) triggers translational repression of the target mRNA. Here, we provide evidence that human Argonaute 2 targets cap-binding protein (CBP)80/20-bound mRNAs and exon junction complex-bound mRNA...

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Autores principales: Choe, Junho, Cho, Hana, Lee, Hyung Chul, Kim, Yoon Ki
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868547/
https://ncbi.nlm.nih.gov/pubmed/20395958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.44
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