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Nonsense-mediated mRNA decay and development: shoot the messenger to survive?
NMD (nonsense-mediated mRNA decay) is a surveillance mechanism that degrades transcripts containing nonsense mutations, preventing the translation of potentially harmful truncated proteins. Although the mechanistic details of NMD are gradually being understood, the physiological role of this RNA sur...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432441/ https://ncbi.nlm.nih.gov/pubmed/21118115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0381500 |
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