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Protein transduction from retroviral Gag precursors

Retroviral particles assemble a few thousand units of the Gag polyproteins. Proteolytic cleavage mediated by the retroviral protease forms the bioactive retroviral protein subunits before cell entry. We hypothesized that this process could be exploited for targeted, transient, and dose-controlled tr...

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Detalhes bibliográficos
Main Authors: Voelkel, Christine, Galla, Melanie, Maetzig, Tobias, Warlich, Eva, Kuehle, Johannes, Zychlinski, Daniela, Bode, Juergen, Cantz, Tobias, Schambach, Axel, Baum, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867892/
https://ncbi.nlm.nih.gov/pubmed/20385817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914517107
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