Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery

The Sleeping Beauty (SB) transposase and its newly developed hyperactive variant, SB100X, are of increasing interest for genome modification in experimental models and gene therapy. The potential cytotoxicity of transposases requires careful assessment, considering that residual integration events o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Galla, Melanie, Schambach, Axel, Falk, Christine S., Maetzig, Tobias, Kuehle, Johannes, Lange, Kathrin, Zychlinski, Daniela, Heinz, Niels, Brugman, Martijn H., Göhring, Gudrun, Izsvák, Zsuzsanna, Ivics, Zoltán, Baum, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167617/
https://ncbi.nlm.nih.gov/pubmed/21609958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr384
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados