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Protein transduction from retroviral Gag precursors

Retroviral particles assemble a few thousand units of the Gag polyproteins. Proteolytic cleavage mediated by the retroviral protease forms the bioactive retroviral protein subunits before cell entry. We hypothesized that this process could be exploited for targeted, transient, and dose-controlled tr...

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Autors principals: Voelkel, Christine, Galla, Melanie, Maetzig, Tobias, Warlich, Eva, Kuehle, Johannes, Zychlinski, Daniela, Bode, Juergen, Cantz, Tobias, Schambach, Axel, Baum, Christopher
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867892/
https://ncbi.nlm.nih.gov/pubmed/20385817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914517107
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