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Protein transduction from retroviral Gag precursors

Retroviral particles assemble a few thousand units of the Gag polyproteins. Proteolytic cleavage mediated by the retroviral protease forms the bioactive retroviral protein subunits before cell entry. We hypothesized that this process could be exploited for targeted, transient, and dose-controlled tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Voelkel, Christine, Galla, Melanie, Maetzig, Tobias, Warlich, Eva, Kuehle, Johannes, Zychlinski, Daniela, Bode, Juergen, Cantz, Tobias, Schambach, Axel, Baum, Christopher
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867892/
https://ncbi.nlm.nih.gov/pubmed/20385817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914517107
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