Dexamethasone stimulates store-operated calcium entry and protein degradation in cultured L6 myotubes through a phospholipase A(2)-dependent mechanism

Muscle wasting in various catabolic conditions is at least in part regulated by glucocorticoids. Increased calcium levels have been reported in atrophying muscle. Mechanisms regulating calcium homeostasis in muscle wasting, in particular the role of glucocorticoids, are poorly understood. Here we te...

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Main Authors: Itagaki, Kiyoshi, Menconi, Michael, Antoniu, Bozena, Zhang, Qin, Gonnella, Patricia, Soybel, David, Hauser, Carl, Hasselgren, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
Assuntos:
Muscle Cell Biology and Cell Motility
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867385/
https://ncbi.nlm.nih.gov/pubmed/20107037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00309.2009
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