Dexamethasone stimulates store-operated calcium entry and protein degradation in cultured L6 myotubes through a phospholipase A(2)-dependent mechanism

Muscle wasting in various catabolic conditions is at least in part regulated by glucocorticoids. Increased calcium levels have been reported in atrophying muscle. Mechanisms regulating calcium homeostasis in muscle wasting, in particular the role of glucocorticoids, are poorly understood. Here we te...

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Autors principals: Itagaki, Kiyoshi, Menconi, Michael, Antoniu, Bozena, Zhang, Qin, Gonnella, Patricia, Soybel, David, Hauser, Carl, Hasselgren, Per-Olof
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
Matèries:
Muscle Cell Biology and Cell Motility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867385/
https://ncbi.nlm.nih.gov/pubmed/20107037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00309.2009
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