Dexamethasone stimulates store-operated calcium entry and protein degradation in cultured L6 myotubes through a phospholipase A(2)-dependent mechanism

Muscle wasting in various catabolic conditions is at least in part regulated by glucocorticoids. Increased calcium levels have been reported in atrophying muscle. Mechanisms regulating calcium homeostasis in muscle wasting, in particular the role of glucocorticoids, are poorly understood. Here we te...

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Bibliographic Details
Main Authors: Itagaki, Kiyoshi, Menconi, Michael, Antoniu, Bozena, Zhang, Qin, Gonnella, Patricia, Soybel, David, Hauser, Carl, Hasselgren, Per-Olof
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
Subjects:
Muscle Cell Biology and Cell Motility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867385/
https://ncbi.nlm.nih.gov/pubmed/20107037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00309.2009
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