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RESVERATROL PREVENTS DEXAMETHASONE-INDUCED EXPRESSION OF THE MUSCLE ATROPHY-RELATED UBIQUITIN LIGASES ATROGIN-1 AND MURF1 IN CULTURED MYOTUBES THROUGH A SIRT1-DEPENDENT MECHANISM
Resveratrol (3,5,4’-trihydroxystilbene) has been ascribed multiple beneficial biological effects but the influence of resveratrol on glucocorticoid-induced muscle atrophy is not known. We examined the effects of resveratrol on dexamethasone-induced atrogin-1 and MuRF1 expression, FOXO1 acetylation,...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261799/ https://ncbi.nlm.nih.gov/pubmed/22166204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.11.154 |
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