RESVERATROL PREVENTS DEXAMETHASONE-INDUCED EXPRESSION OF THE MUSCLE ATROPHY-RELATED UBIQUITIN LIGASES ATROGIN-1 AND MURF1 IN CULTURED MYOTUBES THROUGH A SIRT1-DEPENDENT MECHANISM

Resveratrol (3,5,4’-trihydroxystilbene) has been ascribed multiple beneficial biological effects but the influence of resveratrol on glucocorticoid-induced muscle atrophy is not known. We examined the effects of resveratrol on dexamethasone-induced atrogin-1 and MuRF1 expression, FOXO1 acetylation,...

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Detalhes bibliográficos
Main Authors: Alamdari, Nima, Aversa, Zaira, Castillero, Estibaliz, Gurav, Aniket, Petkova, Victoria, Tizio, Steven, Hasselgren, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261799/
https://ncbi.nlm.nih.gov/pubmed/22166204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.11.154
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