DEXAMETHASONE AND CORTICOSTERONE INDUCE SIMILAR, BUT NOT IDENTICAL, MUSCLE WASTING RESPONSES IN CULTURED L6 AND C2C12 MYOTUBES

Dexamethasone-treated L6 (a rat cell line) and C2C12 (a mouse cell line) myotubes are frequently used as in vitro models of muscle wasting. We compared the effects of different concentrations of dexamethasone and corticosterone (the naturally occurring glucocorticoid in rodents) on protein breakdown...

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Detalhes bibliográficos
Main Authors: Menconi, Michael, Gonnella, Patricia, Petkova, Victoria, Lecker, Stewart, Hasselgren, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901105/
https://ncbi.nlm.nih.gov/pubmed/18615595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21833
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